Cystic Fibrosis Mice Are Highly Susceptible to Repeated Acute Pseudomonas aeruginosa Pneumonia after Intranasal Inoculation

Figure 7

Single-cell RNA sequencing analysis of lung macrophage cells. (a) Heatmap of lung macrophage differentially expressed genes (DEGs). (b) The number of up- and downregulated DEGs. (c) Upregulated DEGs in CF and non-CF lung macrophages were subjected to KEGG pathway analysis and presented as bubble enrichment maps. (d) Downregulated DEGs in CF and non-CF lung macrophages were subjected to KEGG pathway analysis and presented as bubble enrichment maps.

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