Identification of Novel Molecular and Clinical Biomarkers of Survival in Glioblastoma Multiforme Patients: A Study Based on The Cancer Genome Atlas Data

Table 1

Cox regression performed on the top ten signalling pathways determined for the methylation data.

Signalling pathway		SE	value	HR	95% CI for HR
					Lower	Upper
Neuroactive ligand-receptor interaction	0.031	0.014	0.029	1.032	1.003	1.061
Staphylococcus aureus infection	0.003	0.011	0.799	1.003	0.981	1.026
Cytokine-cytokine receptor interaction	-0.033	0.017	0.055	0.968	0.936	1.001
Hematopoietic cell lineage	0.022	0.011	0.057	1.022	0.999	1.045
Complement and coagulation cascades	-0.008	0.010	0.413	0.992	0.973	1.011
Viral protein interaction with cytokine and cytokine receptor	0.004	0.015	0.792	1.004	0.975	1.033
Legionellosis	-0.002	0.007	0.777	0.998	0.984	1.012
Amoebiasis	0.025	0.011	0.016	1.026	1.005	1.047
Serotonergic synapse	-0.014	0.009	0.122	0.986	0.968	1.004
cAMP signalling pathway	-0.023	0.012	0.061	0.977	0.954	1.001
Age (years)	0.039	0.006	<0.001	1.040	1.027	1.053