Research Article

Identification of Novel Molecular and Clinical Biomarkers of Survival in Glioblastoma Multiforme Patients: A Study Based on The Cancer Genome Atlas Data

Table 2

Cox regression performed on the top ten signalling pathways determined for the expression data.

Signalling pathwaySE valueHR95% CI for HR
LowerUpper

Neuroactive ligand-receptor interaction-0.0070.0250.7920.9930.9461.043
Staphylococcus aureus infection0.0000.0220.9951.0000.9581.043
Cytokine-cytokine receptor interaction-0.0130.0280.6400.9870.9341.043
Hematopoietic cell lineage0.0130.0220.5581.0130.9711.057
Complement and coagulation cascades0.0230.0180.2061.0230.9881.060
Viral protein interaction with cytokine and cytokine receptor0.0020.0180.9071.0020.9671.038
Legionellosis-0.0230.0180.2080.9770.9431.013
Amoebiasis0.0140.0200.4771.0150.9751.056
Serotonergic synapse-0.0480.0260.0670.9530.9051.003
cAMP signalling pathway0.0340.0300.2571.0340.9761.096
0.0390.010<0.0011.0401.0191.060