In Silico Approach Triterpene Glycoside of <i>H. atra</i> Targeting Orotidine 5-Monophosphate Decarboxylase Protein (PfOMPDC) in <i>P. falciparum</i> Infection Mechanism

<div>(a) The RMSD of 17-hydroxyfuscocineroside B in comparison with orotidine-5<span class="nowrap"><svg height="7.86364pt" id="M134" style="vertical-align:-0.04981995pt" version="1.1" viewbox="-0.0498162 -7.81382 4.53621 7.86364" width="4.53621pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M295 534L291 558C277 573 202 603 180 597L75 72L120 51L295 534Z"></path></g></svg>-</span>monophosphate as a control. (b) The number of hydrogen bonds of 17-hydroxyfuscocineroside B in comparison with orotidine-5<span class="nowrap"><svg height="7.86364pt" id="M135" style="vertical-align:-0.04981995pt" version="1.1" viewbox="-0.0498162 -7.81382 4.53621 7.86364" width="4.53621pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M295 534L291 558C277 573 202 603 180 597L75 72L120 51L295 534Z"></path></g></svg>-</span>monophosphate as a control. (c) The total energy of 17-hydroxyfuscocineroside B in comparison with orotidine-5<span class="nowrap"><svg height="7.86364pt" id="M136" style="vertical-align:-0.04981995pt" version="1.1" viewbox="-0.0498162 -7.81382 4.53621 7.86364" width="4.53621pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M295 534L291 558C277 573 202 603 180 597L75 72L120 51L295 534Z"></path></g></svg>-</span>monophosphate as a control. (d) The radius of gyration of 17-hydroxyfuscocineroside B in comparison with orotidine-5<span class="nowrap"><svg height="7.86364pt" id="M137" style="vertical-align:-0.04981995pt" version="1.1" viewbox="-0.0498162 -7.81382 4.53621 7.86364" width="4.53621pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M295 534L291 558C277 573 202 603 180 597L75 72L120 51L295 534Z"></path></g></svg>-</span>monophosphate as a control.</div>

BioMed Research International

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Figure 4

Figure 4: In Silico Approach Triterpene Glycoside of <i>H. atra</i> Targeting Orotidine 5-Monophosphate Decarboxylase Protein (PfOMPDC) in <i>P. falciparum</i> Infection Mechanism 

Figure 4 | In Silico Approach Triterpene Glycoside of H. atra Targeting Orotidine 5-Monophosphate Decarboxylase Protein (PfOMPDC) in P. falciparum Infection Mechanism 