Citrus limon (L.) Osbeck Fruit Peel Extract Attenuates Carbon Tetrachloride-Induced Hepatocarcinogenesis in Sprague-Dawley Rats

Figure 5

Effect of LPE on serum concentrations of alpha- (α-) fetoprotein (AFP) (a) and C-reactive protein (AFP) (b). Control group received olive oil (5 mL/kg ip) in the morning twice a week for 16 weeks. The model group received CCl₄/olive oil (2 mL/kg ip) in the morning twice a week for 16 weeks. LPE and capecitabine groups received CCl₄/olive oil (2 mL/kg ip) in the morning and, respectively, LPE (50, 100, and 200 mg/kg po) and capecitabine (100 mg/kg po) in the afternoon twice a week for 16 weeks. Each value is the , . , Control vs. model; ^#, LPE and capecitabine vs. model. LPE: Citrus limon fruit feel extract.

(a)

(b)