Research Article

Effect of DNMT3A R882H Hot Spot Mutations on DDX43 Promoter Methylation in Acute Myeloid Leukemia

Table 3

The distribution of DNMT3A R882H mutated/unmutated patients and healthy controls in DDX43 promoter methylation groups.

SamplesDDX43 promoter methylation (%) value
0-2525-5050-7575-100

Patients
 Without R882H mutation25530
 With R882H mutation1310.020a
 Total38530
Controls330.035b

Chi-squared. aComparison between patients with R882H mutations and those without this mutation. bComparison between total number of patients and controls.