Regional MRI Perfusion Measures Predict Motor/Executive Function in Patients with Clinically Isolated Syndrome
Table 1
Clinical, demographic, and neuropsychological information on the patients and healthy controls when appropriate (mean ± SD and range in parentheses).
CIS ()
Controls ()
Gender:
Men
14
25
Women
16
18
Handedness:
Right
27
37
Left
3
6
First symptom:
Optic neuritis
6
—
Brainstem-cerebellar
11
Spinal
1
Sensorimotor
6
Polysymptomatic
6
Age (years)
31.4 ± 9.6 (15–51)
33.6 ± 10.2 (16–54)
Education (years)
13.6 ± 2.6 (6–18)
14.4 ± 3.2 (6–19)
Illness duration (years)
1.5 ± 1.5 (0–5)
—
EDSS
1.0 ± .5 (0–2)
—
WASI Vocabulary (z)
.80 ± 1.0 (−1.5 to 2.5)
.35 ± 0.9 (−1.5 to 2.1)
WASI Matrices (z)
−.25 ± .9 (−2.5 to 1.4)
−.08 ± .8 (−2.2 to 1.6)
CESD
13.0 ± 12.7 (1–49)
—
STAI-B (Trait Anxiety)
44.2 ± 10.6 (26–68)
—
Fatigue
29.7 ± 11.2 (10–50)
—
EDSS: Expanded Disability Status Scale; CESD: Center for Epidemiological Studies Depression Scale; STAI-A: State-Trait Anxiety Inventory Form Y; Fatigue: Fatigue Severity Scale; WASI: Wechsler Abbreviated Scale of Intelligence. Standard () scores on neuropsychological tests.
