Hypomania, Depression, Euthymia: New Evidence in Parkinson’s Disease

Table 4

Comparisons of ISS subscales, NMSS, and QUIP scores between the groups of subjects.

	DN,	DRT-patients (n-MF+MF),	n-MF,	MF,	Controls,	(d.f.)	value
ISS_ACT	180.0 (96.5, 250.5)	173.5 (102.0, 249.5)	155.0 (100.0, 210.0)	191.0 (133.0, 262.0)	142.0 (94.0, 233.0)	2.5 (3)	0.47
ISS_WB	161.0 (101.3, 189.8)	197.0 (120.0, 236.0)	199.5 (135.0, 235.0)	185.0 (95.0, 237.0)	175.5 (131.0, 231.0)	4.86 (3)	0.18
ISS_PC	99.0 (32.0, 195.0)	71.0 (20.0, 119.0)	68.0 (0.0, 102.0)	80.5 (36.0, 139.0)	102.0 (53.0, 153.0)	5.32 (3)	0.15
ISS_DI	25.0 (10.0, 97.0)	22.5 (1.0, 57.0)	15.0 (0.0, 50.0)	35.0 (7.0, 68.0)	19.0 (6.0, 65.0)	4.04 (3)	0.26
NMSS	10.5 (2.0, 21.0)	24.0 (9.5, 42.0)	19.0 (6.0, 34.3)	30.0 (14.8, 59.8)	—	-23.08 (2)	0.003
QUIP_ICDs	0/21 (0)	27/72 (38)	12/42 (29.3)	17/30 (50)	—	14.89 (2)	<0.0001
QUIP_other	4/21 (19.1)	19/72 (26.8)	10/42 (24.4)	9/30 (30)	—	4.86 (2)	0.301
QUIP_medication	0/21 (0)	7/72 (9.9)	3/42 (7.3)	4/30 (13.3)	—	3.13 (2)	0.209

Data are reported as median (lower quartile, upper quartile) or n/total (%). Legend: ISS_ACT: Internal State Scale’s Activation subscale; ISS_WB: Internal State Scale’s Well Being subscale; ISS_PC: Internal State Scale’s Perceived Conflict subscale; ISS_DI: Internal State Scale’s Depression Index subscale; NMSS: Non-Motor Symptoms Scale; QUIP_ICDs: QUIP part 1 about ICDs (gambling, sexual behavior, buying, and eating); QUIP_other: QUIP part 2 about additional questions for hobbyism, punding, and walkabout; QUIP_medication: QUIP part 3 about compulsive medication use. Significant values are in bold. Asymptotic significance and test’s value adapted after Bonferroni’s post hoc correction.