Research Article

Association between Genetic Variants in DUSP15, CNTNAP2, and PCDHA Genes and Risk of Childhood Autism Spectrum Disorder

Table 3

Genotype distributions and corresponding risk predictions for ASD under genetic models of inheritance.

SNPModelGenotypeCases
(%)
Controls
(%)
OR (95% CI) value

rs3746599DominantA/A89 (44.3)71 (35.5)
A/G+G/G112 (55.7)129 (64.5)0.69 (0.46-1.04)0.0731
RecessiveA/A+A/G169 (84.1)174 (87.0)
G/G32 (15.9)26 (13.0)1.27 (0.72-2.22)0.4065

rs7794745DominantA/A60 (29.9)77 (38.5)
A/T+T/T141 (70.2)123 (61.5)1.47 (0.97-12.23)0.0684
RecessiveA/A+A/T162 (80.6)172 (86.0)
T/T39 (19.4)28 (14.0)1.48 (0.87-2.51)0.1485

rs251379DominantG/G64 (31.8)69 (34.5)
A/A+A/G137 (68.2)131 (65.5)1.12 (0.74-1.69)0.5719
RecessiveA/G+G/G156 (77.6)160 (80.0)
A/A45 (22.4)40 (20.0)1.15 (0.71-1.85)0.5591

OR: odds ratio; CI: confidence interval.