Research Article
Association between Genetic Variants in DUSP15, CNTNAP2, and PCDHA Genes and Risk of Childhood Autism Spectrum Disorder
Table 3
Genotype distributions and corresponding risk predictions for ASD under genetic models of inheritance.
| SNP | Model | Genotype | Cases (%) | Controls (%) | OR (95% CI) | value |
| rs3746599 | Dominant | A/A | 89 (44.3) | 71 (35.5) | | | A/G+G/G | 112 (55.7) | 129 (64.5) | 0.69 (0.46-1.04) | 0.0731 | Recessive | A/A+A/G | 169 (84.1) | 174 (87.0) | | | G/G | 32 (15.9) | 26 (13.0) | 1.27 (0.72-2.22) | 0.4065 |
| rs7794745 | Dominant | A/A | 60 (29.9) | 77 (38.5) | | | A/T+T/T | 141 (70.2) | 123 (61.5) | 1.47 (0.97-12.23) | 0.0684 | Recessive | A/A+A/T | 162 (80.6) | 172 (86.0) | | | T/T | 39 (19.4) | 28 (14.0) | 1.48 (0.87-2.51) | 0.1485 |
| rs251379 | Dominant | G/G | 64 (31.8) | 69 (34.5) | | | A/A+A/G | 137 (68.2) | 131 (65.5) | 1.12 (0.74-1.69) | 0.5719 | Recessive | A/G+G/G | 156 (77.6) | 160 (80.0) | | | A/A | 45 (22.4) | 40 (20.0) | 1.15 (0.71-1.85) | 0.5591 |
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OR: odds ratio; CI: confidence interval.
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