Attenuation of Strychnine-Induced Epilepsy Employing Amaranthus viridis L. Leaves Extract in Experimental Rats

Table 1

Side effects of various anti-epileptic drugs.

Drug	The main side effects	Important but very rare side effects	Reference
Topiramate	Cognitive difficulties, tremors, dizziness, ataxia, headache, fatigue, gastrointestinal upset, and renal calculi		Dichter and Brodie [12]
Tiagabine	Confusion, dizziness, gastrointestinal upset, anorexia, and fatigue
Oxcarbazepine	Dizziness, diplopia, ataxia, headache, weakness, rash, and hyponatremia
Zonisamide	Somnolence, headache, dizziness, ataxia, and renal calculi
Vigabatrin	Behavioural changes, depression, sedation, fatigue, weight gain, and gastrointestinal upset	Psychosis
Clobazam	Sedation, dizziness, irritability, depression, and disinhibition
Felbamate	Irritability, insomnia, anorexia, nausea, and headache	Aplastic anaemia and hepatic failure
Lamotrigine	Rash, dizziness, tremor, ataxia, diplopia, headache, and gastrointestinal upset	Stevens–Johnson syndrome
Gabapentin	Somnolence, fatigue, ataxia, dizziness, and gastrointestinal upset
Phenytoin	Phenytoin encephalopathy, psychosis, locomotor dysfunction, hyperkinesia, megaloblastic anaemia, decreased bone mineral content, Stevens–Johnson syndrome, toxic epidermal necrolysis, immunoglobulin. A deficiency, gingival hyperplasia, dress syndrome (drug reaction accompanied by eosinophilia and systemic symptoms), cardiovascular collapse, hypotension, arrhythmias, hydantoin syndrome in newborns, and purple glove syndrome