Cucurbita maxima Seeds Reduce Anxiety and Depression and Improve Memory

Table 10

Effect of C. maxima seed extracts on depression by forced swim test and tail suspension test.

Groups and doses (mg/kg)	Forced swim test		Tail suspension test
	Immobility time (seconds) 22nd day	% Reduction immobility	Immobility time (seconds) 22nd day	% Reduction immobility
Control		—		—
C. maxima 50	**	36	**	34.3
C. maxima 100	**	35.4	**	35.4
C. maxima 200	**	49.3	**	42
Diazepam 3		9.19		2.5
Imipramine 30	**	54.1	**	52.5

, average ± SEM; * substantial; ** greatly substantial in comparison with control.