Establishing an OCD Model in BALB/c Mice Using RU24969: A Molecular and Behavioural Study of Optimal Dose Selection

Table 2

Results of RT-qPCR analyses of Gabra and serotonin transporter gene expression in various mouse groups.

Group	Conc. of RU24969 injected (mg/kg)	Number of mice	Gene expression fold increase (+)/decrease (-)
			Gabra1	Serotonin transporter
A	0	6	1.00	1.00
B	5	6	+1.02^1,2	-1.88
C	10	6	+1.17^2	-3.97
D	15	6	-1.01^1,2	-1.68
E	20	6	-2.35^1	-5.28
SEM	—	—	0.081	0.412

^1,2Means in a column with different numerical superscripts are significantly different (). SEM = standard error of the mean.