Serum Prolidase Activity and Oxidative Stress in Diabetic Nephropathy and End Stage Renal Disease: A Correlative Study with Glucose and Creatinine

Table 1

Representation of clinical parameters and demography for controls and cases.

Parameter	Control-1	Control-2	Case-1	Case-2	ANOVA (/Sig.)
Number of subjects (total 229 subjects)	50	50	86	43	⋯
Sex (F = female, M = male)	F-20	F-16	F-39	F-19	⋯
	M-30	M-34	M-47	M-24
Age mean (in years)	52.64 ± 18.76	53.34 ± 14.68	52.34 ± 12.89	57.34 ± 15.36	= 1.16; = 0.326
Duration of T2DM (in years)	Nil	7.18 ± 3.22	11.14 ± 3.18	16.46 ± 3.09	= 100.45; 0.001
Fasting blood glucose (FBS), mg/dL	125.32 ± 43.91	191.26 ± 38.24	193.87 ± 42.27	218.91 ± 39.54	= 46.01; 0.001
Postprandial blood glucose (PPBS), mg/dL	130.68 ± 47	236.68 ± 53.89	236.17 ± 23.79	255.84 ± 37.30	= 102.58; 0.001
Serum creatinine, mg/dL	1.07 ± 0.34	1.91 ± 0.43	2.74 ± 0.60	6.05 ± 1.92	= 241.73; 0.001
Glomerular filtration rate (GFR), mL/min/1.7 m^2	86.13 ± 11.47	72.96 ± 16.14	41.59 ± 12.45	15.73 ± 6.31	= 320.75; 0.001
Blood pressure (mm Hg)
Systolic	127.52 ± 11.17	136.63 ± 7.85	138.94 ± 7.14	152.74 ± 9.47	= 64.99; 0.001
Diastolic	81.50 ± 6.87	85.53 ± 7.63	87.53 ± 9.02	88.65 ± 7.79	= 7.83; 0.001
Haemoglobin, g/dL	12.79 ± 1.39	11.56 ± 1.30	9.59 ± 1.71	8.86 ± 2.00	= 63.66; 0.001
Blood urea, mg/dL	31.16 ± 14.24	49.66 ± 9.72	89.10 ± 23.40	128.98 ± 32.41	= 192.86; 0.001