Cetuximab and Cisplatin Show Different Combination Effect in Nasopharyngeal Carcinoma Cells Lines via Inactivation of EGFR/AKT Signaling Pathway

Figure 2

Cetuximab enhanced cisplatin-induced apoptosis and antiproliferation effect in HNE1 cells. HNE1 cells were treated with cetuximab, cisplatin, or the double agents for 48 h before the cells were analysed by flow cytometry ((a), (b), (c), and (d)). Multiplication capacity of cells in different treatment groups is shown in ((e), (f)) via a colony formation assay. versus cisplatin treatment alone.

(a) CNE2

(b) HNE1

(c) CNE2

(d) HNE1

(e)

(f)