Synthesis and Evaluation of In Vitro Antibacterial and Antitumor Activities of Novel N,N-Disubstituted Schiff Bases

Figure 6

Effects of the three N,N-disubstituted Schiff bases on the cell cycle of leukemia and prostate cells. K562 and HEL leukemia cell lines (a) and one prostate cancer cell line PC3 and prostate mesenchymal cell line BPH1 (b) were used for assaying the cell cycle change by the treating with the active compounds, and then, the date were analyzed to obtain the more intuitive results (c and d). Compounds 1a, 1b, and 1c were assayed at the concentration of 20 μmol/L. Data represent the mean ± standard deviation of three independent experiments. ; .

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