Research Article

The Safety and Efficiency of Tirofiban in Acute Ischemic Stroke Patients Treated with Mechanical Thrombectomy: A Multicenter Retrospective Cohort Study

Table 2

Operational details and operative period managements.

CharacteristicTirofiban group N = 89Control group N = 85 value

Pre rt-PA27 (30.3)22 (25.9)0.514
OTP time, median (IQR), min345 (244.0–419.5)258.5 (194.0–322.7)0.000
Local anesthesia63 (70.8)70 (82.4)0.072
ASITN/SIR (1-2)73 (82.0)66 (77.6)0.472
Number of passes, median (IQR)2 (1–3)2 (1–2)0.738
Balloon angioplasty27 (30.3)6 (7.1)0.000
Permanent stenting21 (23.6)7 (8.2)0.006
mTICI ≥ 2b68 (76.4)48 (56.5)0.005

Operative period antiplatelet
None14 (15.7)36 (42.4)0.000
Aspirin/clopidogrel22 (24.7)27 (31.8)
Aspirin + clopidogrel53 (59.6)22 (25.9)

Postoperative treatment
Anticoagulation17 (19.1)38 (44.7)0.000
Sedation29 (32.6)14 (16.5)0.014
Dehydration64 (71.9)55 (64.7)0.307

Data are number, number (%), median (IQR), or mean (SD). OTP time indicated time from onset to groin puncture.