Physiochemical, Insecticidal, and Antidiabetic Activities of Senna occidentalis Linn Root
Table 6
Effects of Senna occidentalis (L.) Roots of 80% ethanolic extracts on glucose-loaded rats.
Treatments
Bloods glucose levels mg/dl mean ± S. D.
Time
Groups and dose
0 h
1 hours
2 hours
4 hours
Group I “normal vehicle 2% water”
68.33b ± 8.50
63.67c ± 2.52
69.33c ± 11.68
57.67c ± 3.21
Group II glucose loading 2 g/kg body wt “positive control”
89.00a ± 11.27
114.00a ± 13.11
138.33a ± 13.32
132.67a ± 30.75
Group III glucose loading 2 g/kg + standard glibenclamide 10 mg/kg.
93.67a ± 11.6 (5.25%)
75.67b,c ± 14.15 (−33.62%)
62.00b,c ± 7.81 (−55.18%)
57.33b,c ± 3.79 (−56.79%)
Group VI glucose loading 2 g/kg + EtOH of S. o roots 200 mg/kg.
101.6a ± 18.4 (14.15%)
47.6b,c ± 15.6 (−58.25%)
80.33c ± 4.5 (−41.93%)
68.2b,c ± 6.9 (−48.59%)
n = 6, a = <0.05 indicates a significant difference compared with diabetic control; b = () indicates a significant difference compared with diabetic control; c = () indicates a significant difference compared with standard drug (glibenclamide), % = level2-level1/level1X100 compared with diabetic control. S. o=Senna occidentalis.