Diverse Effect of Vitamin C and N-Acetylcysteine on Aluminum-Induced Eryptosis

Figure 5

The effects of various concentrations of AlCl₃ on intracellular Ca²⁺ levels in the erythrocytes. (a) Histogram of Fluo₃-fluorescence of the erythrocytes following exposure for 24 hours to Ringer solution without (control; grey area) and with the presence of 30 μM (black line) and 100 μM of AlCl₃μM (dotted line) and 1 µM of ionomycin (positive control; dashed line). (b) Arithmetic means ± SD of the percentage of erythrocyte with enhanced Fluo₃-fluorescence following treatment with various concentrations of AlCl₃ and ionomycin (1 µM), in Ringer solution for 24 hours. , , and  < 0.001 significant difference compared to control groups.

(a)

(b)