Identification of Prognostic Genes in Neuroblastoma in Children by Weighted Gene Coexpression Network Analysis

Table 2

Functional enrichment of genes in brown coexpression modules.

Ontology	ID	Description	. adjusted	Count
BP	GO: 0006397	mRNA processing	4.74E − 44	72
BP	GO: 0008380	RNA splicing	1.00E − 33	59
BP	GO: 0034660	ncRNA metabolic process	2.81E − 31	58
BP	GO: 0090501	RNA phosphodiester bond hydrolysis	2.81E − 31	36
BP	GO: 0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	5.58E − 24	44
BP	GO: 0000398	mRNA splicing, via spliceosome	5.58E − 24	44
BP	GO: 0000375	RNA splicing, via transesterification reactions	7.78E − 24	44
BP	GO: 0090305	Nucleic acid phosphodiester bond hydrolysis	3.29E − 22	38
BP	GO: 0006401	RNA catabolic process	5.85E − 22	43
BP	GO: 0034470	ncRNA processing	6.99E − 21	38
CC	GO: 0035770	Ribonucleoprotein granule	1.85E − 21	32
CC	GO: 0036464	Cytoplasmic ribonucleoprotein granule	3.32E − 19	29
CC	GO: 0005840	Ribosome	4.00E − 13	27
CC	GO: 0044391	Ribosomal subunit	3.19E − 12	22
CC	GO: 0000313	Organellar ribosome	1.05E − 11	16
CC	GO: 0005761	Mitochondrial ribosome	1.05E − 11	16
CC	GO: 0000932	P-body	3.01E − 11	14
CC	GO: 0005759	Mitochondrial matrix	1.94E − 10	31
CC	GO: 0043186	P granule	1.58E − 08	7
CC	GO: 0045495	Pole plasm	1.58E − 08	7
MF	GO: 0140098	Catalytic activity, acting on RNA	2.44E − 27	45
MF	GO: 0004540	Ribonuclease activity	2.04E − 17	23
MF	GO: 0004518	Nuclease activity	1.40E − 16	28
MF	GO: 0003730	mRNA 3’-UTR binding	3.19E − 13	17
MF	GO: 0004519	Endonuclease activity	3.73E − 13	20
MF	GO: 0045182	Translation regulator activity	6.87E − 12	14
MF	GO: 0140101	Catalytic activity, acting on a tRNA	1.73E − 10	17
MF	GO: 0003729	mRNA binding	2.02E − 10	33
MF	GO: 0003725	Double-stranded RNA binding	2.18E−10	14
MF	GO: 0004521	Endoribonuclease activity	2.76E − 10	13