Antidiarrheal and Antisecretory Effect of 80% Hydromethanolic Leaf Extract of Moringa stenopetala Baker f. in Mice

Table 1

The effect of 80% methanol leaf extract of M. stenopetala in the castor oil-induced diarrhea model.

Group	Stool frequency	Stool score	The onset of diarrhea (minutes)	% inhibition of frequency of defecation	% delay of onset of diarrhea
Vehicle	16.50 ± 1.43	1.83 ± 0.14	48.17 ± 8.53	—	-
LOP3	4.50 ± 0.85	1.54 ± 0.19	122.17 ± 19.49	72.7	60.5
MS150	8.50 ± 1.12	1.33 ± 0.18	62.33 ± 22.83	48.5	22.7
MS300	6.83 ± 0.65	0.79 ± 0.11	111.60 ± 27.67	58.6	56.8
MS450	6.50 ± 1.52	1.08 ± 0.20	107.17 ± 17.19	60.6	55.1

All values are expressed as mean ± standard error of the mean (n = 6); < 0.05 compared to the negative control, Vehicle = 2% tween 80, LOP3 = loperamide 3 mg/kg, MS150 = 150 mg/kg of M. stenopetala extract, MS300 = 300 mg/kg of M. stenopetala extract, and MS450 = 450 mg/kg of M. stenopetala extract.