Research Article

Screening of Antimicrobial Properties and Bioactive Compounds of Pleurotus Ostreatus Extracts against Staphylococcus Aureus, Escherichia coli, and Neisseria Gonorrhoeae

Table 2

MBC determined for P. ostreatus mushroom extracts antimicrobial properties against target bacteria.

P. ostreatus mushroom extracts

Isolate IDABCDNPS
S. aureus (ATCC 25923)1 × 10−3 mg/ml1 × 10−6 mg/ml1 × 10−1 mg/ml1 × 10−5 mg/ml1 × 10−4 mg/ml
E. coli (ATCC 25922)1 × 10−2 mg/ml1 × 10−4 mg/ml1 × 10−3 mg/ml1 × 10−5 mg/ml1 × 10−5 mg/ml
N. gonorrhoeae (ATCC 49926)1 × 10−3 mg/ml1 × 10−5 mg/ml1 × 10−2 mg/ml1 × 10−4 mg/ml1 mg/ml
ISID 41 × 10−3 mg/ml1 × 10−3 mg/ml1 × 10−4 mg/ml1 × 10−6 mg/ml1 × 10−3 mg/ml
ISID 51 × 10−3 mg/ml1 × 10−5 mg/ml1 × 10−2 mg/ml1 × 10−5 mg/ml1 × 10−4 mg/ml
ISID 71 × 10−2 mg/ml1 × 10−5 mg/ml1 × 10−1 mg/ml1 × 10−6 mg/ml1 × 10−2 mg/ml
ISID 171 × 10−4 mg/ml1 × 10−6 mg/ml1 × 10−3 mg/ml1 × 10−4 mg/ml1 × 10−3 mg/ml
ISID 261 × 10−2 mg/ml1 × 10−3 mg/ml1 × 10−2 mg/ml1 × 10−4 mg/ml1 mg/ml
ISID 281 × 10−4 mg/ml1 × 10−3 mg/ml1 × 10−5 mg/ml1 × 10−4 mg/ml1 × 10−1 mg/ml
ISID 391 × 10−4 mg/ml1 × 10−4 mg/ml1 × 10−3 mg/ml1 × 10−5 mg/ml1 × 10−2 mg/ml
ISID 451 × 10−3 mg/ml1 × 10−4 mg/ml1 × 10−4 mg/ml1 × 10−6 mg/ml1 mg/ml
ISID 551 × 10−2 mg/ml1 × 10−3 mg/ml1 × 10−2 mg/ml1 × 10−3 mg/ml1 × 10−3 mg/ml

P. ostreatus extracts revealed varying degrees of antibacterial activity against the pathogens examined (Table 2). The majority of clinical samples were shown to be most susceptible to extracts B and D and least susceptible to extracts C and NPS.