MicroRNA-Based Markers of Oral Tongue Squamous Cell Carcinoma and Buccal Squamous Cell Carcinoma: A Systems Biology Approach

Figure 2

Seven clusters were identified by the MCODE plugin within the PIM associated with the pathogenesis of OTSCC and BSCC. The network was built based on validated targets of common DEMs in two subtypes of OSCC. MCODE, molecular complex detection; PIM, protein interaction map; OTSCC, oral tongue squamous cell carcinoma; BSCC, buccal squamous cell carcinoma; DEM, differentially expressed miRNA.