Plasminogen Activator Inhibitor-Type I Gene Deficient Mice Show Reduced Influx of Neutrophils in Ventilator-Induced Lung Injury
Figure 4
Pulmonary levels of tumor necrosis factor α (TNF), interleukin- (IL-) 6, macrophage inflammatory protein- (MIP-) 2, and keratinocyte-derived chemokine (KC) in lung tissue homogenate in anesthetized nonventilated control (C) mice, mice ventilated with LVT or HVT. Mice were either PAI-1 deficient (PAI-1−/−, open symbols) or wild type (Wt, closed symbols). Data are represented as individual data with a median. * indicates statistical significant difference compared to Wt.
