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| Criteria | Specific question |
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| 1 | Was the study population described (inclusion and exclusion criteria included)? |
| 2 | Is there a description of the sampling (e.g., consecutive patients, if not why not?)? |
| 3 | Is it clear whether the tests were done prospectively or retrospectively? |
| 4 | Is there a description of the response test (including fluid bolus)? |
| 5 | Is there a detailed description of the equipment and techniques used in the tests? |
| 6 | Is the rationale for cut-offs and ranges given? |
| 7 | Is there detail of the operators in terms of number and training? |
| 8 | Is there detail of what information was available to the readers of the response ? |
| 9 | Were the statistical methods for comparing diagnostic accuracy detailed? |
| 10 | Are there details of tests of reproducibility? |
| 11 | Are the patient demographics and comorbidities shown? |
| 12 | Is there detail of those meeting inclusion criteria but not undergoing either test? |
| 13 | Was there detail of the interval between predictive and response tests? |
| 14 | Is there a report cross-tabulating predictive and response test results? |
| 15 | Is diagnostic accuracy described, including likelihood ratios or data to calculate them? |
| 16 | Is there mention of how missing values were dealt with (i.e., unobtainable values)? |
| 17 | Are the estimates of accuracy variability between operators/readers included? |
| 18 | Are there estimates of reproducibility? |
| 19 | Is the clinical applicability of the study findings discussed? |
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