Research Article

Goal-Directed Fluid Therapy Using Stroke Volume Variation Does Not Result in Pulmonary Fluid Overload in Thoracic Surgery Requiring One-Lung Ventilation

Table 3

Metabolic data. ScvO2: central venous oxygen saturation; BE: base excess. *Difference to BL in analysis of variance (ANOVA) ( ). BL: directly after induction of anesthesia; OLVimpl15: 15 minutes after beginning OLV; OLVterm15: 15 minutes after cessation of OLV; 6postop: 6 hours after surgery; 12postop: 12 hours after surgery; 24postop: 24 hours after surgery.

BLOLVimpl15OLVterm156postop12postop24postop

LactateT [mmol/L]0.8 ± 0.30.8 ± 0.21.1 ± 0.51.2* ± 0.61.1* ± 0.41.2* ± 0.4
LactateL [mmol/L]0.8 ± 0.40.7 ± 0.21 ± 0.50.9 ± 0.31 ± 0.41.1 ± 0.4
LactateE [mmol/L]0.8 ± 0.20.9 ± 0.21.2 ± 0.51.4 ± 0.6*1.2 ± 0.4*1.2 ± 0.3*

ScvO2T [%]84.6 ± 6.585.7 ± 5.686.8 ± 4.876.9 ± 4.9*72.7 ± 8.3*72.6 ± 9.0*
ScvO2L [%]87.0 ± 5.487.3 ± 4.987.5 ± 4.676.8 ± 4.9*74.8 ± 2.9*74.0 ± 6.7*
ScvO2E [%]82.9 ± 6.784.6 ± 6.086.3 ± 5.177.0 ± 5.171.7 ± 10*72.0 ± 10.1*

BET [mmol/L] −5.1 ± 3.3*−6.3 ± 3.3*−5.5 ± 2.6*−5.8 ± 2.1*−5.5 ± 1.9*
BEL [mmol/L] −3.2 ± 2.6*−4.5 ± 2.0*−4.4 ± 1.8*−4.7 ± 2.3*−4.7 ± 2*
BEE [mmol/L] −6.3 ± 3.1*−7.5 ± 3.5*−6.3 ± 2.8*−6.4 ± 1.9*−5.8 ± 1.9

HbT [mg/dL]10.5 ± 1.79.1 ± 1.9*8.5 ± 1.5*9.0 ± 1.5*8.8 ± 1.4*8.7 ± 1.4*
HbL [mg/dL]11.0 ± 1.89.3 ± 2.0*8.8 ± 1.8*8.8 ± 1.9*8.4 ± 2.0*8.2 ± 1.8
HbE [mg/dL] 10.2 ± 1.69.0 ± 1.88.3 ± 1.3*9.2 ± 1.29.0 ± 1.1*9.0 ± 1.0*