Research Article
Improved Outcome of Severe Acute Pancreatitis in the Intensive Care Unit
Table 1
Baseline characteristics and outcomes.
| | Parameter | Prevalence () |
| | Male gender (%) | 31 (62%) | | Mean age (SD; range) | 51.7 (14.8; 16–85) | | Past Medical History | | | Pancreatitis | 40% | | Diabetes mellitus | 24% | | Gallstone disease | 16% | | Liver cirrhosis | 8% | | Chronic kidney disease | 8% | | Transplantation | 4% | | Aetiology of severe pancreatitis | | | Alcohol | 40% | | Gallstone disease | 30% | | Drug induced | 6% | | Hypocalcaemia | 4% | | Post ERCP | 2% | | Hypertriglyceridemia | 2% | | Idiopathic | 16% | | Transfer from other hospital | 48% | | Severity of illness on admission to ICU | | | APACHE II score, median (IQR) | 17 (12–19) | | SOFA, median (IQR) | 5 (3–8) | | POP, median (IQR) | 8 (5–12) | | CTSI, median (IQR) | 4 (2–7.5) | | Associated organ failure | | | AKI | 54% | | ALI | 56% | | IAH | 20% | | Need for respiratory support | 78% | | Need for RRT | 44% | | Treatment with vasoactive drugs | 62% | | Nutrition | | | TPN | 20% | | Enteral nutrition only | 80% | | Interventional treatment | | | Drain insertion | 24% | | Surgical intervention | 26% | | Embolisation | 7.5% | | Outcome | | | ICU mortality | 16% | | Hospital mortality | 20% | | LOS in ICU, median (IQR) | 13.5 (6–30) | | LOS in Hospital, median (IQR) | 30 (16–70) | | Diabetes mellitus in hospital survivors | 11 of 40 survivors | | End stage renal failure in hospital survivors | 2 of 40 survivors |
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ICU: intensive care unit; ERCP: Endoscopic Retrograde Cholangiopancreatography; SD: standard deviation; IQR: interquartile range; APACHE: Acute Physiology and Chronic Health Evaluation; SOFA: sequential organ failure assessment; POP: pancreatitis outcome prediction; CTSI: Computed Tomography Severity Index; AKI: acute kidney injury; ALI: acute lung injury; IAH: intraabdominal hypertension; RRT: renal replacement therapy; TPN: total parenteral nutrition; LOS: length of stay.
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