Clinical Survey of Decreased Blood Flow Rate in Continuous Renal Replacement Therapy: A Retrospective Observational Study

Table 4

Clinical factors associated with the development of the decreased blood flow rate, evaluated by multivariate Cox regression analyses.

	Multivariate analysis
	HR	95% CI	value
Model 1
Age	1.01	0.99–1.03	0.32
Male	1.07	0.57–2.00	0.84
SOFA score	1.04	0.96–1.13	0.33
Catheter position (jugular vein)	0.62	0.29–1.33	0.22
ACT	1.00	0.99–1.01	0.69
Model 2
Age	1.02	0.99–1.04	0.07
Height	1.02	0.99–1.05	0.19
SOFA score	1.04	0.96–1.14	0.34
Catheter position (jugular vein)	0.53	0.25–1.15	0.11
Hb	1.13	0.99–1.28	0.05
Model 3
Age	1.02	0.99–1.04	0.17
Height	1.02	0.99–1.05	0.22
SOFA score	1.04	0.95–1.13	0.45
Catheter position (jugular vein)	0.60	0.28–1.28	0.19
Alb	1.11	0.73–1.68	0.64
Model 4
Age	1.02	0.99–1.04	0.17
Height	1.02	0.99–1.05	0.23
SOFA score	1.03	0.95–1.12	0.50
Catheter position (jugular vein)	0.59	0.28–1.27	0.18
Sepsis or severe infectious diseases	0.90	0.48–1.67	0.72
Model 5
Age	1.02	0.99–1.04	0.16
Height	1.02	0.99–1.05	0.18
SOFA score	1.03	0.95–1.12	0.50
Catheter position (jugular vein)	0.61	0.28–1.30	0.20
Heart failure	0.82	0.44–1.54	0.54
Model 6
Age	1.02	0.99–1.04	0.17
Height	1.02	0.99–1.05	0.19
SOFA score	1.03	0.94–1.12	0.57
Catheter position (jugular vein)	0.59	0.28–1.26	0.18
CVVHDF	1.13	0.51–2.52	0.76

ACT, activating coagulation time; Alb, albumin; CI, confidence interval; CVVHDF, continuous venovenous hemodiafiltration; Hb, hemoglobin; HD, hemodialysis; HR, hazard ratio; SOFA score, sequential organ failure assessment score.