Early Driving Pressure Changes Predict Outcomes during Venovenous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome

Table 5

Factors associated with mortality.

	Univariate logistic regression		Multivariate logistic regression
	Odds ratio (95% CI)	value	Odds ratio (95% CI)	value
paO2/FiO2ratio before VV-ECMO	0.988 (0.97 to 1.01)	0.2079
Serum lactate
Before ECMO	1.12 (0.89 to 1.41)	0.3463
12 h after ECMO	1.12 (0.92 to 1.37)	0.2529
Etiology of ARDS
Bacterial infection versus noninfectious	0.19 (0.04 to 0.74)	0.0338	0.09 (0.01 to 0.97)	0.0099
Viral infection versus noninfectious	0.19 (0.04 to 0.74)	0.0161	0.08 (0.01 to 0.42)	0.0021
Bacterial versus viral infection	1.02 (0.24 to 4.22)	0.9830
Driving pressure
Before ECMO	0.94 (0.84 to 1.05)	0.2770
12 h after ECMO	1.25 (1.05 to 1.48)	0.0129
Absolute change	0.82 (0.71 to 0.94)	0.0048
Relative change (per 1% decrease)	0.96 (0.93 to 0.99)	0.0033	0.94 (0.90 to 0.97)	<0.0001