Research Article
Diabetic Ketoacidosis Updates: Titratable Insulin Infusions and Long-Acting Insulin Early
Table 3
Standard overlap vs. early addition of long-acting insulin to infusion.
| | Baseline characteristics | | Standard (n = 61) | Early insulin overlap (n = 49) | value |
| | Age (years), mean (SD) | 42.2 ± 21.2 | 35.4 ± 16.3 | 0.07 | | Sex (% male) | 55.7 | 26.5 | <0.01 | | Weight (kg), mean (SD) | 75.6 ± 18.7 | 79.2 ± 25.6 | 0.40 | | Lactate (mmol/L), mean (SD) | 3.0 ± 3.1 | 2.7 ± 1.7 | 0.58 | | Creatinine (mg/L), mean (SD) | 1.3 ± 0.6 | 1.3 ± 0.9 | 0.74 | | Type 1 DM (%) | 52.5 | 52.1 | 0.96 | | Ventilated (%) | 11.5 | 6.1 | 0.33 | | pH mean (SD) | 7.27 ± 0.1 | 7.27 ± 0.1 | 0.79 | | A1C mean (SD) | 11.2 ± 2.4 | 12.1 ± 2.4 | 0.08 | | Bicarbonate (mmol/L), mean (SD) | 13.1 ± 6.0 | 15.5 ± 7.8 | 0.07 | | Serum ketones (mmol/L), mean (SD) | 5.2 ± 3.5 | 4.4 ± 3.4 | 0.25 | | Anion gap, mean (SD) | 27.2 ± 8.2 | 25.1 ± 6.8 | 0.15 | | WBC (bil/L). mean (SD) | 13.5 ± 7.2 | 13.9 ± 7.6 | 0.78 |
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SD. standard deviation; n, number.
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