Change in Antimicrobial Therapy Based on Bronchoalveolar Lavage Data Improves Outcomes in ICU Patients with Suspected Pneumonia

Table 4

Outcome measures of intubated versus nonintubated patients based on BAL report-directed antimicrobial modification.

	Not intubated		value	Intubated		value
	Antimicrobial modified			Antimicrobial
				Modified
	Yes (N = 65)	No (N = 21)		Yes (N = 48)	NO (N = 16)
Duration-related outcomes
Total duration of hospital stay (median, (IQR))	17 (13–25)	21 (15–37)	0.200	15 (11.5–24)	20 (14.5–35)	0.123
Total duration of ICU stay (median, (IQR))	10 (7–16)	15 (12–35)	0.001	10 (8–15)	11 (6.5–22.5)	0.641
Duration from admission to FB (median, (IQR))	7 (3–11)	8 (5–11)	0.860	5 (3–8)	5.5 (4.5–11.5)	0.483
Duration from FB to discharge from ICU (median, (IQR))	6 (4–10)	10 (4–12)	0.201	5 (3–9)	6 (5–10)	0.291
Duration from FB to discharge from hospital (median, (IQR))	6 (4–11)	9 (5–15)	0.080	6 (3.5–9.5)	6 (5–12)	0.435
Clinical outcomes ^#
Expired, n (%)	8 (12.3)	5 (23.8)	0.03	15 (31.2)	7 (43.8)	0.33^#
Improved, n (%)	54 (83.1)	12 (57.2)		28 (58.3)	6 (37.5)
Unchanged, n (%)	3 (4.6)	4 (19)		5 (10.5)	3 (18.7)

Mann–Whitney U test; ^#chi-square test. IQR: interquartile range.