Plasma KL-6 as a Potential Biomarker for Bronchopulmonary Dysplasia in Preterm Infants

Table 1

Perinatal characteristics of the patients.

Characteristics	No/mild BPD (n = 48)		Moderate/severe BPD (n = 47)		value
	Mean	SD	Mean	SD
Weight (g)	935.52	160.36	800.64	161.89	<0.001
GA (wks)	26.58	0.77	26.00	0.91	<0.001
Mechanical ventilation (d)	12.96	8.84	34.43	22.34	<0.001
O2 therapy (d)	34.00	17.65	54.33	21.74	<0.001
Hospital stay (d)	64.60	14.63	90.55	26.82	<0.001
CPAP, NIV (d)	10.31	5.14	15.42	8.91	0.048
	n	%	n	%
Percentage <26 + 0 wks GA	15	27.1	29	57.2	0.077
C-section	33	68.8	34	72.3	0.823
Antenatal steroids	42	87.5	33	70.2	0.047
Maternal hypertension	8	16.7	8	17.0	1.000
Chorioamnionitis, pPROM	28	58.3	24	51.1	0.539
Apgar score <3 at 1 min	13	27.1	16	34.0	0.509
RDS III-IV gr	42	87.5	46	97.9	0.111
Surfactant applied	48	100.0	47	100.0	NA
PDA, lung hemorrhage	2	4.2	13	27.7	0.002
Sepsis	6	12.5	11	23.4	0.190
NEC	1	2.1	6	12.8	0.059
ROP	19	39.6	37	82.2	<0.001

SD, standard deviation; GA, gestational age; NIV, noninvasive ventilation, pPROM, preterm premature rupture of membranes; PDA, persistent ductus arteriosus; RDS, respiratory distress syndrome; NEC, necrotizing enterocolitis; ROP, retinopathy of prematurity.