Plasma KL-6 as a Potential Biomarker for Bronchopulmonary Dysplasia in Preterm Infants

Table 2

Area under the curve (AUC), values, cutoff values, and values of screening test validation criteria for KL-6, mechanical ventilation, GA, weight, model 7d, and model 14d.

Characteristics	AUC	value	Cutoff	Sensitivity	Specificity	Positive predictive value	Negative predictive value	Accuracy
KL-6/7d	0.66	0.007	≥247.5	81	52	62	74	66
KL-6/14d	0.75	<0.001	≥277.5	60	85	80	68	73
MV (days)	0.84	<0.001	≤20	77	81	80	78	79
GA (weeks)	0.69	0.001	≤26.5	66	73	70	69	69
Weight (g)	0.73	<0.001	≤855	66	71	69	68	68
Model 7d	0.86	<0.001	≥0.34	79	79	79	79	79
Model 14d	0.91	<0.001	≥0.37	89	81	82	89	85

MV, mechanical ventilation; GA, gestational age.