Plasma KL-6 as a Potential Biomarker for Bronchopulmonary Dysplasia in Preterm Infants

Table 4

OR and 95% CI of prognostic factors for severe/moderate BPD based on KL-6/14d.

Independent variables	Comparison	Crude		Multivariate
		OR (95% CI)		OR (95% CI)
KL-6/14d (U/ml)	≥277.5/<277.5	8.63	(3.20–23.25)	13.59	(3.19–57.96)
PDA, lung hemorrhage	Yes/No	8.79	(1.86–41.57)	23.34	(2.14–254.24)
Mechanical ventilation (d)	≥20/<20	14.18	(5.27–38.19)	4.45	(1.23–16.16)
GA (weeks)	≤26.5/>26.5	5.22	(2.17–12.54)	4.58	(1.16–18.06)
Antenatal steroids	Yes/No	0.34	(0.12–0.97)	0.19	(0.04–0.95)
Sex	Female/Male	0.81	(0.36–1.81)	0.30	(0.08–1.12)
Weight (g)	≤855/>855	4.71	(1.98–11.20)
C-section	Yes/No	1.19	(0.49–2.88)
Complicated pregnancy	Yes/No	0.76	(0.19–3.04)
Apgar score <3 at 1 min	Yes/No	1.39	0.58–3.34

PDA, persistent ductus arteriosus; GA, gestational age.