Research Article

Comparison of Treatment Approaches and Subsequent Outcomes within a Pulmonary Embolism Response Team Registry

Table 3

Secondary outcome 2 (major bleeding) by predictors and outcomes of interest.

No bleeding (N = 1702)Major bleeding (N = 130)Overall (N = 1832)Difference t-test or chi-square, value

PE severity at presentation, N (%)
High risk102 (6.0%)37 (28.5%)139 (7.6%)<0.001
Intermediate-high risk661 (38.8%)46 (35.4%)707 (38.6%)
Intermediate-low risk931 (54.7%)46 (35.4%)977 (53.3%)
Low risk8 (0.5%)1 (0.8%)9 (0.5%)

Bleeding risk assessment, N (%)
High220 (12.9%)28 (21.5%)248 (13.5%)0.028
Moderate857 (50.4%)58 (44.6%)915 (49.9%)
Low625 (36.7%)44 (33.8%)669 (36.5%)

PE severity/bleeding risk assessment profile, N (%)
High-risk PE/high bleeding risk24.0 (1.4%)10.0 (7.7%)34 (1.9%)<0.001
High-risk PE/moderate bleeding risk52 (3.1%)10 (7.7%)62 (3.4%)
High-risk PE/low bleed risk26 (1.5%)17 (13.1%)43 (2.3%)
Intermediate-high PE/high bleeding risk99 (5.8%)14 (10.8%)113 (6.2%)
Intermediate-high PE/moderate bleeding risk334 (19.6%)21 (16.2%)355 (19.4%)
Intermediate-high PE/low bleeding risk228 (13.4%)11 (8.5%)239 (13.0%)
Intermediate-low PE/high bleeding risk97 (5.7%)4 (3.1%)101 (5.5%)
Intermediate-low PE/moderate bleeding risk468 (27.5%)26 (20.0%)494 (27.0%)
Intermediate-low PE/low bleeding risk374 (22.0%)17 (13.1%)391 (21.3%)

Outcomes
Death73 (4.3%)21 (16.2%)94 (5.1%)<0.001
Clinical deterioration160 (9.4%)58 (44.6%)218 (11.9%)<0.001

The percentages within each cell were calculated by using the N in the column header for that cell.