The Effects of Pitavastatin on Nuclear Factor-Kappa B and ICAM-1 in Human Saphenous Vein Graft Endothelial Culture

Table 7

Comparison of ICAM-1 absolute pixel density between experimental groups.

Comparison Groups	P Value
Control x Low Dose Pitavastatin	0.133
Control x High Dose Pitavastatin	0.006
Control x TNF-α	0.004
Control x Low Dose Pitavastatin + TNF-α	0.001
Control x High Dose Pitavastatin + TNF-α	0.001
Control x DMSO	0.032
Low Dose Pitavastatin x High Dose Pitavastatin	0.028
Low Dose Pitavastatin x TNF-α	0.003
Low Dose Pitavastatin x Low Dose Pitavastatin + TNF-α	0.001
Low Dose Pitavastatin x High Dose Pitavastatin + TNF-α	0.001
Low Dose Pitavastatin x DMSO	0.565
High Dose Pitavastatin x TNF-α	0.006
High Dose Pitavastatin x Low Dose Pitavastatin + TNF-α	0.002
High Dose Pitavastatin x High Dose Pitavastatin + TNF-α	0.003
High Dose Pitavastatin x DMSO	0.123
Low Dose Pitavastatin + TNF-αx TNF-α	0.386
Low Dose Pitavastatin + TNF-αx High Dose Pitavastatin + TNF-α	0.624
Low Dose Pitavastatin + TNF-αx DMSO	0.001
High Dose Pitavastatin + TNF-αx TNF-α	0.814
High Dose Pitavastatin + TNF-αx DMSO	0.001
TNF-α x DMSO	0.003

ICAM-1, intercellular adhesion molecule-1; TNF-α, tumor necrosis factor-α; DMSO, dimethyl sulfoxide.