The Relation between Volume and Outcome of Transcatheter and Surgical Aortic Valve Replacement: A Systematic Review and Meta-Analysis

Table 2

Results of sensitivity and subgroup analyses.

Procedure	Subgroup	Odd ratio (95% CI)	value
TAVR	Population period		0.61
	Data before 2010 included	0.43 (0.34, 0.51)
	Data before 2010 excluded	0.46 (0.25, 0.66)
TAVR	Region		0.93
	USA	0.44 (0.34, 0.53)
	Europe	0.42 (0.26, 0.59)
	North and South America and Europe	0.44 (0.23, 0.64)
TAVR	Data type		0.53
	Administrative	0.44 (0.34, 0.54)
	Clinical	0.42 (0.29, 0.55)
TAVR	Cut-off for lowest volume		0.93
	<50	0.44 (0.34, 0.53)
	≥50	0.43 (0.3, 0.56)
	Cut-off for highest volume		0.89
	<100	0.41 (0.32, 0.51)
	≥100	0.48 (0.34, 0.62)
TAVR	Outcome		0.78
	In-hospital mortality	0.43 (0.35,0.52)
	30-day mortality	0.44 (0.23,0.64)
SAVR	Population period		0.84
	Data before 2000 included	0.73 (0.71, 0.74)
	Data before 2010 excluded	0.72 (0.66, 0.77)
SAVR	Cut-off for lowest volume		0.6
	<100	0.71 (0.65, 0.76)
	≥100	0.73 (0.72, 0.75)
	Cut-off for highest volume		0.1
	<100	0.63 (0.53, 0.74)
	≥100	0.73 (0.72, 0.75)