Therapeutic Anticoagulation with Argatroban and Heparins Reduces Granulocyte Migration: Possible Impact on ECLS-Therapy?

Table 2

Comparison of numbers between tracked and expected granulocytes per track length category: number of tracks of the UFH group shows the greatest deviations compared to the control group.

Number of tracked granulocytes in categorized migration distances (track length)
Total track length (μm)			11-50	51-100	101-150	151-200	201-250	>250	Total	Mean
Observation groups	Control	Number of tracks	2042	1220	722	371	174	128	4657	776.2
		Expected number	2208.2	1218.5	663.2	317.9	150.2	99.0	4657	776.2
		Difference (%)	-7.53	0.12	8.86	16.7	15.9	29.3	63.4	10.6
	Argatroban	Number of tracks	2184	1131	608	299	144	96	4462	743.7
		Expected number	2115.8	1167.5	635.5	304.6	143.9	94.8	4462.1	743.7
		Difference (%)	3.23	-3.13	-4.32	-1.82	0.08	1.24	-4.72	-0.79
	Enoxaparin	Number of tracks	1642	1020	519	218	106	59	3564	594
		Expected number	1690.0	932.6	507.6	243.3	114.9	75.7	3564.1	594
		Difference (%)	-2.84	9.38	2.25	-10.4	-7.77	-22.1	-31.5	-5.25
	UFH	Number of tracks	558	175	81	37	13	5	869	144.8
		Expected number	412.1	227.4	123.8	59.3	28.0	18.5	869.1	144.8
		Difference (%)	35.4	-23.0	-34.5	-37.6	-53.6	-72.9	-186.2	-31.0