Aldosterone Blockade in Acute Myocardial Infarction: A Systematic Review and Meta-Analysis

Table 3

Other statistical results of the meta-analysis for comparison between the two groups.

						Heterogeneity
Outcomes	Trials		RR/MD	95% CI	value	(%)	value
Deaths due to HF	5	9259	0.77	(0.61, 0.97)	0.03	0	0.80
Serum potassium level (mmol/l)	9	2949	0.14	(0.06, 0.23)	0.001	93	<0.001
Serum creatinine level (mg/dl)	7	2733	0.02	(0.00, 0.04)	0.02	69	0.004
Hypokalemia	3	7702	0.42	(0.19, 0.95)	0.04	64	0.06
LVEF (%)	7	1754	2.69	(2.44, 2.93)	<0.001	36	0.15
LVEDVI (ml/m^2)	6	1246	-3.19	(-4.97, -1.41)	<0.001	0	0.49
LVESVI (ml/m^2)	6	1270	-4.52	(-8.21, -0.83)	0.02	96	<0.001
LVEDD (cm)	4	854	-0.11	(-0.22, 0.00)	0.05	60	0.06
LVESD (cm)	4	854	-0.15	(-0.43, 0.14)	0.31	93	<0.001
E/A ratio	4	1200	0.15	(0.10, 0.19)	<0.001	55	0.06
EDT (m/s)	4	1200	6.25	(3.25, 9.26)	<0.001	0	0.46

: number; MD: mean difference; RR: relative ratio; CI: confidence interval; : inconsistency index; HF: heart failure; LVEF: left ventricular ejection fraction; LVEDVI: left ventricular end-diastolic volume index; LVESVI: left ventricular end-systolic volume index; LVEDD: left ventricular end-diastolic diameter; LVESD: left ventricular end-systolic diameter; E/A: mitral diastolic early flow velocity E to mitral late flow velocity A; EDT: E-wave deceleration time.