Influence of NQO1 Polymorphisms on Warfarin Maintenance Dose: A Systematic Review and Meta-Analysis (rs1800566 and rs10517)

Table 2

The mean values of warfarin dose for each genotype and comparison of the effect of variant NQO1 rs1800566 genotypes on warfarin dosage requirement in Asian and all populations.

Groups	All population		value	Asian population		value
	MDWD	WMD (95% CI)		MDWD	WMD
CC		—	—		—	—
CT		—	—		—	—
TT		—	—		—	—
CT vs. CC	—	13% (3, 22%)	0.01	—	12% (3, 22%)	0.01
TT vs. CC	—	5% (-64%, 74%)	0.89	—	7% (-66%, 79%)	0.86
CT vs. TT	—	-4% (-58%, 50%)	0.88	—	-6% (-63%, 50%)	0.82
T carriers vs. CC	—	11% (-15%, 37%)	0.39	—	8% (-21%, 37%)	0.60

MDWD: mean daily warfarin dosages; WMD: weighted mean differences; CI: confidence interval; the inverse variance method was used in all comparisons of weight in each study.