Association between Platelet to Neutrophil Ratio (PNR) and Clinical Outcomes in STEMI Patients after Successful pPCI: A Secondary Analysis Based on a Cohort Study
Table 1
Clinical characteristic of participants.
PNR
Q1 (7.09-22.83)
Q2 (22.90-31.46)
Q3 (31.49-43.15)
Q4 (43.41-78.74)
value
value
Age (years, )
0.941
0.941
Gender (male, n (%))
86 (74.14%)
85 (73.91%)
84 (73.04%)
99 (85.34%)
0.085
—
HBP (n, %)
72 (62.07%)
70 (60.87%)
59 (51.30%)
63 (54.31%)
0.286
—
DM (n, %)
38 (32.76%)
41 (35.65%)
30 (26.09%)
40 (34.48%)
0.409
—
Myocardial infarction history (n, %)
14 (12.07%)
15 (13.04%)
10 (8.70%)
16 (13.79%)
0.644
—
Anterior wall myocardial infarction (n, %)
60 (51.72%)
45 (39.13%)
64 (55.65%)
61 (52.59%)
0.062
—
SBP (mmHg, )
0.371
0.347
HR (bpm, )
0.582
0.571
WBC (×109/L, )
<0.001
<0.001
Neutrophil (%, )
<0.001
<0.001
Hemoglobin (g/L, )
0.863
0.860
Platelet (×109/L, )
<0.001
<0.001
PNR
<0.001
<0.001
BUN (mmol/L, )
0.703
0.680
Creatinine (mmol/L, )
0.473
0.839
eGFR (,)
0.935
0.940
Uric acid (mmol/L, )
0.591
0.556
Albumin (g/L, )
0.029
0.040
FBG (mmol/L, )
0.309
0.275
TG (mmol/L, median (quartile))
1.06 (0.61-1.56)
1.00 (0.52-1.42)
0.98 (0.59-1.54)
1.07 (0.60-1.63)
0.378
0.752
TC (mmol/L, )
0.477
0.344
HDL-C (mmol/L, )
0.646
0.496
LDL-C (mmol/L, )
0.018
0.012
Peak cTnI (ng/mL, median (quartile))
17.45 (6.01-29.92)
15.20 (3.97-30.00)
12.50 (3.45-26.90)
11.05 (4.62-30.40)
0.376
0.337
Peak CK-MB (U/L, median(quartile))
128.50 (63.50-215.50)
112.00 (46.50-186.00)
105.00 (37.50-182.50)
94.50 (36.75-196.00)
0.085
0.050
D-Dimer (mg/L, median (quartile))
1.10 (0.40-1.80)
0.90 (0.20-1.60)
0.90 (0.20-1.50)
0.80 (0.20-1.70)
0.915
0.764
LVEDD (mm, )
0.335
0.262
Apelin-12 change rate (%, median (quartile))
12.00 (6.45-20.05)
14.70 (5.35-20.60)
15.50 (6.85-21.65)
13.45 (4.72-20.15)
0.451
0.472
Apelin-12 (ng/mL, )
0.792
0.708
Culprit vessels (n, %)
0.254
—
LAD
62 (53.45%)
52 (45.22%)
59 (51.30%)
58 (50.00%)
LCX
22 (18.97%)
23 (20.00%)
14 (12.17%)
13 (11.21%)
RCA
32 (27.59%)
40 (34.78%)
42 (36.52%)
45 (38.79%)
Stent number ()
0.504
0.655
Pathological Q wave (n, %)
57 (49.14%)
57 (49.57%)
53 (46.09%)
55 (47.41%)
0.949
—
(n, %)
34 (29.31%)
19 (16.52%)
34 (29.57%)
25 (21.55%)
0.055
—
GENSINI
0.360
0.361
MACE (n, %)
33 (28.45%)
27 (23.48%)
28 (24.35%)
30 (25.86%)
0.834
—
Survival time (months, median (quartile))
25.04 (6.20-28.61)
27.72 (15.79-29.25)
23.12 (0.84-26.62)
21.38 (0.51-25.82)
0.228
0.006
Abbreviations: BUN: blood urea nitrogen; CK-MB: creatine kinase MB; cTnI: cardiac troponin I; eGFR: estimated glomerular filtration rate; FBG: fasting blood glucose; HDL-C: high-density lipoprotein cholesterol; LAD: left anterior descending branch; LCX: left circumflex coronary artery; LDL-C: low-density lipoprotein cholesterol; LVEDD: left ventricular and diastolic diameter; MACEs: major adverse cardiovascular events; MI: myocardial infarction; RCA: right coronary artery; SBP: systolic blood pressure; TC: total cholesterol; TG: triglyceride; WBC: white blood cells. value calculated by Kruskal-Wallis H test (skewed distribution).
