Exosomes from Bone Marrow Mesenchymal Stem Cells with Overexpressed Nrf2 Inhibit Cardiac Fibrosis in Rats with Atrial Fibrillation

Figure 4

Lv-Nrf2 exosomes suppressed the expression of fibrosis-related markers in AF rats. (a) Masson stains for evaluating left atrial fibrosis within rats from each group. . (b) Quantification for the atrial fibrosis region. (c–h) The representative immunohistochemical staining and quantitative analysis showing the expression of atrial fibrosis makers α-SMA (c, d), collage I (e, f), or TGF-β1 (g, h) in the heart of the rats. . /group. Results reflected . , in comparison to the control group. ^#, ^## in comparison to the AF+PBS group.