Research Article
A Study on Weight Loss Cause as per the Side Effect of Liraglutide
Table 1
Baseline characteristics of patients (
).
| | Total | MAIN_SE(-) group | MAIN_SE(+) group | STOP_SE(-) group | STOP_SE(+) group | value |
| | Number (%) | 157 | 41 (26.1) | 23 (14.7) | 63 (40.1) | 30 (19.1) | | | Age (years) | | | | | | 0.486 | | Female sex, (%) | 117 (74.5) | 27 (65.9) | 19 (82.6) | 48 (76.2) | 23 (76.7) | 0.461 | | Weight (kg) | | | | | | 0.640 | | BMI (kg/m2) | | | | | | 0.974 | | Use of liraglutide | | | | | | | | Period of use (month) | | — | — | | | 0.968 | | Dosage (mg) | | | | | | 0.165 | | Present illness | | | | | | | | Hypertension, (%) | 48 (30.6) | 15 (36.6) | 5 (21.7) | 16 (25.4) | 12 (40.0) | 0.309 | | Prediabetes, (%) | 10 (6.4) | 2 (4.9) | 1 (4.4) | 6 (9.5) | 1 (3.3) | 0.716 | | DM, (%) | 57 (36.3) | 15 (36.6) | 10 (43.5) | 20 (31.8) | 12 (40.0) | 0.740 | | Dyslipidemia, (%) | 65 (41.4) | 15 (36.6) | 14 (60.9) | 22 (34.9) | 14 (46.7) | 0.144 | | GI trouble history, (%) | 4 (2.6) | 0 (0.0) | 0 (0.0) | 1 (1.6) | 3 (10.0) | 0.060 | | Fatty liver, (%) | 11 (7.0) | 3 (7.3) | 3 (13.0) | 3 (4.8) | 2 (6.7) | 0.629 | | Thyroid disease, (%) | 1 (0.6) | 0 (0.0) | 0 (0.0) | 1 (1.6) | 0 (0.0) | >0.999 | | Psychiatric history, (%) | 15 (9.6) | 4 (9.8) | 2 (8.7) | 7 (11.1) | 2 (6.7) | 0.979 | | Allergy history, (%) | 1 (0.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (3.3) | 0.338 | | Laboratory finding | | | | | | | | Glucose (mg/dL) | | | | | | 0.938 | | HbA1c (%) | | | | | | 0.823 | | BUN (mg/dL) | | | | | | 0.284 | | Creatinine (mg/dL) | | | | | | 0.096 | | eGFR (mL/min/1.73 m2) | | | | | | 0.263 | | AST (U/L) | | | | | | 0.621 | | ALT (U/L) | | | | | | 0.612 | | ALP (U/L) | | | | | | 0.744 | | γGTP (U/L) | | | | | | 0.722 | | CPK (U/L) | | | | | | 0.249 | | Total cholesterol (mg/dL) | | | | | | 0.307 | | Triglycerides (mg/dL) | | | | | | 0.402 | | HDL-cholesterol (mg/dL) | | | | | | 0.779 | | LDL-cholesterol (mg/dL) | | | | | | 0.669 |
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Categorical variables are reported as frequencies (%), and continuous variables are reported as . AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase; BMI: body mass index; BUN: blood urea nitrogen; CPK: creatinine phosphokinase; DM: diabetes mellitus; eGFR: estimated glomerular filtration rate; GI: gastrointestinal; γ-GTP: γ-glutamyl transpeptidase; HbA1c: glycated hemoglobin; HDL: high-density lipoprotein; LDL: low-density lipoprotein. |
