Cardiovascular Therapeutics / 2022 / Article / Tab 1 / Research Article
A Clinical Nomogram Based on the Triglyceride-Glucose Index to Predict Contrast-Induced Acute Kidney Injury after Percutaneous Intervention in Patients with Acute Coronary Syndrome with Diabetes Mellitus Table 1 Baseline characteristics of the non-CI-AKI group and CI-AKI group.
Variables Non-CI-AKI group ( CI-AKI group ( The subtypes of ACS ( <0.001 UA 491 (57.1%) 70 (32.9%) STAMI 185 (21.5%) 78 (36.6%) NSTAMI 184 (21.4%) 65 (30.5%) Age 65 (56,71) 66 (57,75.5) 0.048 125 (14.5%) 82 (38.5%) <0.001 Gender ( 0.203 Male 537 (62.4%) 143 (67.1%) Female 323 (37.6%) 70 (32.9%) BMI (kg/m2 ) 24.5 (23-26.775) 24.3 (22.75-26.20) 0.178 SBP (mmHg) 134 (124-145) 132 (120-146) 0.264 DBP (mmHg) 79 (72-86) 80 (72-87) 0.323 Smoking ( 0.086 No 677 (78.7%) 156 (73.2%) Yes 183 (21.3%) 57 (26.8%) Drinking ( 0.18 No 738 (85.8%) 175 (82.2%) Yes 122 (14.2%) 38 (17.8%) Past medical history ( Coronary heart disease 837 (97.3%) 203 (95.3%) 0.126 PCI surgery history 505 (58.7%) 130 (61%) 0.539 The recent ACS 192 (22.3%) 46 (21.6.0%) 0.819 History of cerebral infarction 263 (30.6%) 79 (37.1%) 0.068 History of unstable angina 499 (58.0%) 110 (51.6%) 0.092 History of stable angina 7 (0.8%) 0 (0.0%) 0.186 Multivessel coronary artery disease 536 (62.3%) 173 (81.2%) <0.001 Hyperuricemia 242 (28.1%) 94 (44.1%) <0.001 Ischemic stroke 178 (20.7%) 40 (18.8%) 0.533 Peripheral artery stenosis 23 (2.7%) 2 (0.9%) 0.133 Hypertension 474 (55.1%) 131 (61.5%) 0.092 Hyperlipidemia 48 (5.6%) 20 (9.4%) 0.041 Chronic kidney disease 69 (8.0%) 11 (5.2%) 0.155 Family history of CKD 23 (2.7%) 4 (1.9%) 0.506 Culprit vessel ( Left anterior descending 582 (67.7%) 154 (72.3%) 0.193 Left circumflex 341 (39.7%) 84 (39.4%) 0.954 Right coronary artery 394 (45.8%) 98 (46%) 0.959 Left main 3 (0.3%) 2 (0.9%) 0.258 Stent number per patient ( 0.165 1 691 (80.3%) 162 (76.1%) ≥2 169 (19.7%) 51 (23.9%) 454 (52.8%) 128 (60.1%) 0.055 Hematological index LDL-C (mmol/L) 2.015 (1.58-2.6175) 2.7 (2.045-3.39) 0.001 HDL-C (mmol/L) 0.97 (0.81-1.14) 0.93 (0.825-1.145) 0.35 TC (mmol/L) 3.77 (3.1625-4.5075) 3.93 (3.215-4.845) 0.114 TG (mmol/L) 1.4 (1.06-1.9675) 1.61 (1.265-2.285) 0.002 FBG (mmol/L) 7.165 (5.98-8.87) 7.32 (6.455-9.355) 0.006 TyG index <0.001 ≤8.55 163 (19%) 19 (8.9%) 8.556-8.98 243 (28.3%) 53 (24.9%) 8.99-9.39 223 (25.9%) 53 (24.9%) ≥9.40 231 (26.9%) 88 (41.3%) ALT (U/L) 25 (19-37) 29 (16.5-48.5) 0.213 AST (U/L) 32 (18-120) 40 (22-112.5) 0.051 Creatine kinase (U/L) 120 (66-201) 148 (72.5-769.5) 0.061 Troponin (ng/L) 13.4 (3-135.3075) 25.1 (5.62-546) 0.05 HbA1c (%) 7.3 (6.6-8.6) 7.26 (6.61-8.41) 0.656 Scr (umol/L) 62 (53-75) 62 (53-74) 0.693 eGFR (mL/min) 98.365 (90.0025-106.8325) 88.19 (78.81-97.605) <0.001 Medications used before surgery Statin ( 850 (98.8%) 210 (98.6%) 0.769 Ezetimibe ( 159 (18.5%) 35 (16.4%) 0.485 Apolizumab ( 162 (18.8%) 27 (12.7%) 0.035 Aspirin ( 855 (99.4%) 211 (99.1%) 0.562 Clopidogrel ( 293 (34.1%) 82 (38.5%) 0.225 Ticagrelor ( 526 (61.2%) 129 (60.6%) 0.872 ACEI/ARB ( 254 (29.5%) 71 (33.3%) 0.28 ARNI ( 162 (18.8%) 52 (24.4%) 0.068 Beta-blockers ( 584 (67.9%) 136 (63.8%) 0.259 Oral hypoglycemic drugs 500 (58.1%) 110 (51.6%) 0.087 Insulin ( 104 (12.1%) 16 (7.5%) 0.058 Anticoagulant ( 101 (11.7%) 21 (9.9%) 0.438
Abbreviations: UA: unstable angina; STAMI: ST-segment elevation myocardial infarction; NSTAMI: non-ST-segment elevation myocardial infarction; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; PCI: percutaneous coronary intervention; ACS: acute coronary syndrome; CKD: chronic kidney disease, LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; TC: total cholesterol; TG: triglyceride; FBG: fast blood glucose; TyG: triglyceride-glucose; ALT: alanine transaminase; AST: aspartate aminotransferase; HbA1c: glycated hemoglobin A; Scr: serum creatinine; eGFR: estimated glomerular filtration rate; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; ARNI: angiotensin receptor neprilysin inhibitor.
