Cardiovascular Therapeutics / 2022 / Article / Tab 3 / Research Article
A Clinical Nomogram Based on the Triglyceride-Glucose Index to Predict Contrast-Induced Acute Kidney Injury after Percutaneous Intervention in Patients with Acute Coronary Syndrome with Diabetes Mellitus Table 3 Baseline characteristics of training and validation sets.
Variables Training ( Validation set ( The subtypes of ACS ( 0.085 UA 380 (51.0%) 181 (55.2%) STAMI 197 (26.4%) 66 (20.1%) NSTAMI 168 (22.6%) 81 (24.7%) Age 65 (57,73) 64 (56,71) 0.187 153 (20.5%) 54 (16.5%) 0.119 Gender ( 0.905 Male 473 (63.5%) 207 (63.1%) Female 272 (36.5%) 121 (36.9%) BMI (kg/m2 ) 24.5 (22.9-26.7) 24.5 (23.025-27.075) 0.470 SBP (mmHg) 133 (123-146) 135 (122-145) 0.711 DBP (mmHg) 80 (72-86) 79 (71.25-86) 0.419 Smoking ( 0.593 No 575 (77.2%) 258 (78.7%) Yes 170 (22.8%) 70 (21.3%) Drinking ( 0.839 No 635 (85.2%) 278 (84.8%) Yes 110 (14.8%) 50 (15.2%) Past medical history ( Coronary heart disease 730 (98.0%) 310 (94.5%) 0.002 PCI surgery history 455 (61.1%) 180 (54.9%) 0.057 The recent ACS 165 (22.1%) 73 (22.3%) 0.969 History of cerebral infarction 241 (32.3%) 101 (30.8%) 0.614 History of unstable angina 427 (57.3%) 182 (55.5%) 0.578 History of stable angina 5 (0.7%) 2 (0.6%) 0.908 Multivessel coronary artery disease 489 (65.6%) 220 (67.1%) 0.647 Hyperuricemia 231 (31.0%) 105 (32.0%) 0.744 Ischemic stroke 154 (20.7%) 64 (19.5%) 0.664 Peripheral artery stenosis 21 (2.8%) 4 (1.2%) 0.11 Hypertension 420 (56.4%) 185 (56.4%) 0.994 Hyperlipidemia 50 (6.7%) 18 (5.5%) 0.449 Chronic kidney disease 61 (8.2%) 19 (5.8%) 0.169 Family history of CKD 20 (2.7%) 7 (2.1%) 0.596 Culprit vessel ( Left anterior descending 507 (68.1%) 229 (69.8%) 0.566 Left circumflex 287 (38.5%) 138 (42.1%) 0.273 Right coronary artery 350 (47.0%) 142 (43.3%) 0.264 Left main 3 (0.4%) 2 (0.6%) 0.646 Stent number per patient ( 0.11 1 602 (80.8%) 251 (76.5) ≥2 143 (19.2%) 77 (23.5%) 414 (55.6%) 168 (51.2%) 0.188 Hematological index LDL-C (mmol/L) 2.11 (1.605-2.81) 2.1 (1.6425-2.8175) 0.641 HDL-C (mmol/L) 0.97 (0.81-1.14) 0.96 (0.83-1.14) 0.765 TC (mmol/L) 3.79 (3.145-4.545) 3.835 (3.24-4.5375) 0.422 TG (mmol/L) 1.42 (1.07-2) 1.495 (1.11-2.0475) 0.415 FBG (mmol/L) 7.25 (6.115-9.035) 7.14 (6.065-8.8225) 0.748 TyG index 0.71 ≤8.55 131 (17.6%) 51 (15.5%) 8.556-8.98 203 (27.2%) 93 (28.4%) 8.99-9.39 186 (25%) 90 (27.4%) ≥9.40 225 (30.2%) 94 (28.7%) ALT (U/L) 25 (18-39) 25.5 (18-39) 0.629 AST (U/L) 36 (19-117) 30.5 (19-122.75) 0.557 Creatine kinase (U/L) 126 (66-230.5) 119.5 (70-209.25) 0.908 Troponin (ng/L) 14 (3.365-274.5) 14 (3.0475-130.25) 0.592 HbA1c (%) 7.31 (6.61-8.61) 7.21 (6.61-8.4575) 0.596 Scr (umol/L) 62 (53-75) 62 (54-74) 0.565 eGFR (mL/min) 97.1 (86.085-106.08) 96.505 (87.27-105.105) 0.604 Medications used before surgery Statin ( 735 (98.7%) 325 (99.1%) 0.555 Ezetimibe ( 136 (18.3%) 58 (17.7%) 0.822 Apolizumab ( 131 (17.6%) 58 (17.7%) 0.969 Aspirin ( 739 (99.2%) 327 (99.7%) 0.348 Clopidogrel ( 270 (36.2%) 105 (32.0%) 0.181 Ticagrelor ( 442 (59.3%) 213 (64.9%) 0.083 ACEI/ARB ( 225 (30.2%) 100 (30.5%) 0.925 ARNI ( 151 (20.3%) 63 (19.2%) 0.689 Beta-blockers ( 504 (67.7%) 216 (65.9%) 0.564 Oral hypoglycemic drugs 424 (56.9%) 186 (56.7%) 0.95 Insulin ( 83 (11.1%) 37 (11.3%) 0.947 Anticoagulant ( 83 (11.1%) 39 (11.9%) 0.722
Abbreviations: UA: unstable angina; STAMI: ST-segment elevation myocardial infarction; NSTAMI: non-ST-segment elevation myocardial infarction; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; PCI: percutaneous coronary intervention; ACS: acute coronary syndrome; CKD: chronic kidney disease, LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; TC: total cholesterol; TG: triglyceride; FBG: fast blood glucose; TyG: triglyceride-glucose; ALT: alanine transaminase; AST: aspartate aminotransferase; HbA1c: glycated hemoglobin A; Scr: serum creatinine; eGFR: estimated glomerular filtration rate; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; ARNI: angiotensin receptor neprilysin inhibitor.
