Research Article

Effect of Treatment with Colchicine after Acute Coronary Syndrome on Major Cardiovascular Events: A Systematic Review and Meta-Analysis of Clinical Trials

Table 1

Summary of the PICOS criteria used to identify relevant studies.

ParameterDescription

PopulationACS or MI patients of any age
InterventionColchicine
ComparatorPlacebo or control group
OutcomesPrimary composite endpoint (MI and death), MI, stroke, hs-CRP serum level, GI adverse events
Study designRandomized and nonrandomized clinical trials

ACS: acute coronary syndrome; MI: myocardial infarction; hs-CRP: high-sensitivity C-reactive protein; GI: gastrointestinal.