Butein Inhibits Oxidative Stress Injury in Rats with Chronic Heart Failure via ERK/Nrf2 Signaling

Figure 5

Butein activates the ERK/NRF2 pathway. (a) Level of ERK phosphorylation protein and nuclear accumulation of Nrf2 were examined by western blot analysis. (b) Butein-induced HO-1 and GCLC protein expression was further investigated by Western blot analysis.

(a)

(b)