Social App to Improve Warfarin Therapy in Post-MHVR Chinese Patients: A Randomized Controlled Trial
Table 1
Baseline characteristics of the patients.
Characteristic
Social app group
Routine care group
value
Age
Mean age (yrs)
0.14
years (, %)
298 (82.3)
271 (76.1)
0.04
Female (, %)
218 (60.2)
212 (59.6)
0.85
Height (cm)
0.75
Weight (kg)
0.78
Body mass index
1.0
Valve position
AVR (, %)
74 (20.4)
74 (20.8)
0.91
MVR (, %)
165 (45.6)
167 (46.9)
0.72
DVR (, %)
123 (34.0)
115 (32.3)
0.63
Smoker (, %)
102 (28.2)
99 (27.8)
0.91
Medical history
Atrial fibrillation (, %)
182 (50.3)
191 (53.7)
0.37
Diabetes (, %)
14 (3.9)
18 (5.1)
0.47
Hypertension (, %)
62 (17.1)
60 (16.9)
0.92
NYHA (, %)
152 (42.0)
162 (45.5)
0.34
Stroke (, %)
62 (17.1)
63 (17.7)
0.84
VTE (, %)
2 (0.6)
1 (0.3)
0.57
Coronary artery disease (, %)
22 (6.1)
32 (9.0)
0.14
Peripheral arterial disease (, %)
1 (0.3)
3 (0.8)
0.37
Hepatic dysfunction (, %)
14 (3.9)
19 (5.3)
0.38
Renal dysfunction (, %)
7 (1.9)
9 (2.5)
0.65
SAMe-TT2R2 score
0.55
Drug combinations
Aspirin (, %)
28 (7.7)
40 (11.2)
0.11
P2Y12 inhibitor (, %)
3 (0.8)
3 (0.8)
1.00
Amiodarone (, %)
95 (26.2)
117 (32.9)
0.052
Average of INRs
0.005
Warfarin dose
0.24
Frequency of monitoring
<0.001
Self-testing (, %)
113 (31.2)
27 (7.6)
<0.001
Follow-up (days)
0.14
The continuous variables in this table were normally distributed and expressed as . AVR: aortic valve replacement; MVR: mitral valve replacement; DVR: double valve replacement; NYHA: New York Heart Association; VTE: venous thromboembolism; INR: international normalized ratio. The SAMe-TT2R2 score considers the sex, age, medical history, treatment regimen, tobacco use, and race. An INR target of 2.0 (1.5-2.5) for AVR patients and 2.3 (1.8-2.8) for MVR or DVR patients. Average of INRs refers to the average of all the INR results during follow-up period.
