Cardioprotection of mAb2G4/ODN/lip on Myocardial Ischemia-Reperfusion Injury via Inhibiting the NF-κB Signaling Pathway

Figure 5

The cell viability and the expression of inflammatory cytokines in vitro experiments. Effects of ODN/lip and mAb2G4/ODN/lip on cell viability (a) and the expression of LDH (b), MDA (c), IL-6 (d), IL-1β (e), and TNF-α (f) in H/R ventricular myocyte model. Control group (cells were cultured in the normal incubating condition), H/R group (cells were subjected to hypoxia for 2 hours and reoxygenation 1-hour treatment), LO group (treated with 2 μg ODN/lip), HO group (treated with 4 μg ODN/lip), LM group (treated with 2 μg mAb2G4/ODN/lip), and HM group (treated with 4 μg mAb2G4/ODN/lip). Data were expressed as . ^ns, , , , and . H/R group vs. control group; LO group, HO group, LM group, and HM group vs. H/R group; LO group vs. HO group; LM group vs. HM group; LO group vs. LM group.

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