Research Article

Bardoxolone Methyl Ameliorates Myocardial Ischemia/Reperfusion Injury by Activating the Nrf2/HO-1 Signaling Pathway

Figure 5

BARD activates the Nrf2/HO-1 pathway to alleviate myocardial I/R injury. (a) Nrf2 immunohistochemistry staining. (b) HO-1 immunohistochemical staining. (c) The positive cell amounts of Nrf2. (d) The amounts of HO-1-positive cells. (e) Western blot of Nrf2 and HO-1. (f, g) Nrf2 and HO-1 expression levels were determined by western blotting. (h, i) Nrf2 and HO-1 mRNA expression levels were measured by real-time PCR analysis. Magnification of microscope: ×200 and ×400. Scale bar: 50 μm and 100 μm. and .
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