DT-010 Exerts Cardioprotective Effects by Regulating the Crosstalk between the AMPK/PGC-1α Pathway and ERp57

Figure 2

Effect of DT-010 on AMPK/PGC-1α pathway and ERp57 in H9c2 cells. (a–d) DT-010 increased the ERp57 (b), p-AMPKα (c), and PGC-1α (d) protein expression levels in t-BHP-induced H9c2 cell injury. (e) Cell viability (% of Ctrl) was measured by the MTT assay. Data are of two or three independent experiments. and versus the Ctrl group; ^##, ^###, and ^#### versus the t-BHP group. ^$$. Data were analyzed using one-way ANOVA and Dunnett’s multiple comparison test (b–d) or Tukey’s multiple comparison tests (e).

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